The latest webinar series from The Togeth3R Consortium of European 3Rs centres will showcase non-animal approaches in research fields associated with high levels of animal use across four sessions. In each webinar we will hear from three researchers about the scientific benefits and replacement impacts of their models, before a panel discussion where you can ask your questions about developing and using non-animal methods in your field of research. Learn more about the series in our news item: Non-animal approaches across Europe. This webinar explores the development and application of non-animal approaches in oncology, including organoids to study lung cancer and leukaemia, microphysiological systems and using patient samples to improve translation. Oncology is the third highest area of animal use for basic research in the UK and Europe with researchers often relying on animals to investigate how tumours grow and develop new treatments. Programme Wednesday 5 March, 13.00 – 14.20 (GMT)/14.00 – 15.20 (CET) Dr Sanae El Harane – University of Geneva, Switzerland: AirLiwell technology: development and perspectives in oncology replacement. Dr Deepali Pal – University of Bristol, UK: Patient-derived leukaemia organoids. Prof John Greenman – University of Hull, UK: Tissue-on-chip models using patient biopsies to study patient response. A Q&A panel discussion will be facilitated by Dr Jeffrey Bajramovic, Director of the 3Rs Centre Utrecht.