Dr Frances Rawle will provide an overview of the current landscape and pitfalls of ethical review and Dr Stephen Turnock will present his work on creating the ARRIVE study plan, a structured template to promote transparent communication of planned in vivo studies. Lauren Cresser, HOLC and NIO at The Pirbright Institute will showcase their study plan, highlighting the essential information required for the harm benefit review of each study and for the daily organisation of the animal unit.