A 2-day international meeting on Systematic Reviews of Animal studies and in VItro. Our priority topics for discussion include: - The integration of automation and AI in systematic reviews and meta-analyses. - Translational research bridging animal studies to human applications and policy implementation. - Identification and management of questionable research practices and potential research misconduct. The conference will feature a reproducibility challenge, which includes an effort to reproduce various steps of published systematic reviews and offers a prize.